Calcification of the Falx Cerebri: A Comprehensive Overview

Introduction

Calcification of the falx cerebri, a midline structure separating the two cerebral hemispheres, is a common finding in computed tomography (CT) scans. It is typically considered a physiological calcification, meaning it occurs naturally as part of the aging process.

Physiological Calcifications

Physiological calcifications are usually incidental findings on non-contrast CT (NCCT) scans. They are commonly found in various structures, including the falx cerebri, choroid plexus, and pineal gland. These calcifications are typically small, punctate, and symmetrically distributed.

Embryological Derivation

The falx cerebri is derived from embryonic mesenchymal cells. As these cells differentiate, occasional ossification may occur due to friction or hemorrhage. This process can lead to the formation of calcifications within the falx cerebri.

Variants of Calcification

The most common variants of calcification of the falx cerebri are seen in the anterior region, where the falx may be deficient or fenestrated. Abnormalities of the falx, such as calcification, are often associated with other developmental anomalies of the brain.

Clinical Significance

Ossification of the falx cerebri is often an incidental finding and is not associated with any known pathological process. However, in some cases, it may be associated with underlying conditions, such as trauma, infection, or metabolic disorders. In these instances, further investigation is necessary to determine the underlying cause.

Conclusion

Calcification of the falx cerebri is a common finding in CT scans and is generally considered a physiological calcification. It is important for radiologists to be aware of the various variants of calcification and their clinical implications. By understanding the normal range of variations, radiologists can avoid unnecessary further investigation and provide accurate interpretations of CT scans.